Eye Ointments

Composition – Azithromycin 1% w/w

Indications – Bacterial Conjunctivitis, Blepharitis, Bacterial Keratitis.

• Characterized by a broad antimicrobial spectrum
• Safest antibiotics, well tolerated, and has special pharmacokinetic properties.
• Been found to maintain prolonged drug residence time, have a less frequent dosing regimen, thus increasing patient compliance.
• Prolonged high concentrations of azithromycin in conjunctival tissue make this drug suitable for treatment of conjunctivitis caused by chlamydiae and other susceptible organisms.

Presentation- 5 gm

Composition – Dexpanthenol 50 mg

Indications – Epithelial corneal defects, created iatrogenically during surface laser ablation procedure

• Panthenol becomes quickly oxidized to pantothenic acid (vitamin B5) whichis used in the synthesis of coenzyme A and thus is crucial for metabolic functions.
• Effective for the therapyof corneal epithelial defects.

· Necessary in the processes of reconstruction of epithelium, has regenerative and anti-inflammatory properties· Eyes receiving D-panthenol showed  better OF Best corrected visual acuity.( Journal of Ophthalmology Volume 2018, Article ID 6537413, 6 pages)·       Provitamin B5 contained in 5% drops and 5% gel of D-panthenol effectively accelerates the processes of healing the wounds of conjunctiva and cornea.

Presentation- 5 gm

Composition: Moxifloxacin 0.5% w/v, HPMC (Hydroxy Propyl Methyl Cellulose) 0.25% w/v
Indications:
· Bacterial Conjunctivitis
· Keratitis
· Pre and post operative Infections
· Endopthalmitis.
Description:
· As safe in pediatric patients as in non-pediatric patients with bacterial conjunctivitis.
· Unique, preservative free, anti-infective, offers elevated tissue concentrations.
· Has a spectrum of coverage that appropriately encompasses the most common organisms in endophthalimitis.

Presentation- 5 ml

Dosage Form: Eye Drops
How to Use: As directed by Physician

Composition – Gatifloxacin 0.3% w/w

Indications – Bacterial Conjunctivitis, Bacterial Keratitis, Pre and Post Prophylaxis, Corneal Ulcers

• valuable treatment for decreasing the conjunctival bacterial load in patients undergoing cataract surgery.
• Showed goodpenetration into the aqueous of patients at the time of cataract surgery
• there is no ocular toxicity when the drug is given topically and in prescribed concentrations
• Gatifloxacin is safe, and effective against a broad spectrum of bacteria, including intracellular bacteria and anaerobes

Presentation- 5 gm

Composition – Hydroxypropyl Methylcellulose 2% w/w

Indications – Corneal Dehydration, Tear Film Instability, Mild to moderate dry eyes

· 0.5% HPMC provides long coverage of and protection for the ocular surface.·       Used as a matrix that swells and expands after absorbing water and expand the thickness of the tear film·       Showed better film forming properties.·       Due to ease of formulation, ease of installation and better patient compliance, it is a suitable treatment for dry eye syndrome.

Presentation- 5 gm

Composition– Tobramycin 0.3% w/w

Indications-

• Ocular Infection due to Pseudomonas aeruginosa,
• Corneal ulcer,
• Ophthalmia neonatrum blepharitis

Description:

• Safe aminoglycoside than other antibiotics.
• Drug of choice for infants and kids

Presentation- 5 gm

Dosage Form: Eye Drop

How to Use: As directed by physician

Composition –Sodium Chloride 6% w/w
Indications–
Irritation of the cornea with inflammatory & allergic diseases (combined therapy)
Description –
· Creates a hypertonic tear film, thereby drawing water out of the cornea to reduce swelling.
· Decreases swelling of the cornea, may lessen eye discomfort or irritation caused by the swelling.
· Use of Hypertonic sodium chloride 6% ointment at night applied to the conjunctival cul-de-sac limits this build-up of edema.

Presentation-  5 gm

Dosage Form– Eye Ointment.
How to Use – As directed by Physician

 Composition: Chloramphenicol 10 mg, Hydrocortisone Acetate 5 mg.

Indications:

• Treatment of superficial ocular infections involving the conjunctiva and/or the cornea caused by bacteria.

Description:

• Broad-spectrum antibiotic, acts by interfering with bacterial protein synthesis and is mainly bacteriostatic.
• Reduces eye inflammation following eye surgery.

Presentation– 5 gm

Dosage Form: ointment

How to Use: As directed by physician

Composition: Gancyclovir Opthalmic Gel 0.15% w/v, Benzalkonium Chloride

Indications:

• Acute Superficial Herpetic Keratitis,
• Viral Kerato Conjunctivitis.

Description:

• Close the viral chapter
• Intercellular half-life: exceeding 24 hrs
• Conc- 10 folds higher than acyclovir.

Presentation: 5 gm

Dosage Form: Ointment

How to Use: As directed by physician

Composition – Loteprednol Etabonate 5mg

Indications– steroid responsive inflammatory conditions of the palpebral and bulbar conjunctiva, cornea and anterior segment of the globe such as allergic conjunctivitis, acne rosacea, superficial punctate keratitis, herpes zoster keratitis, iritis, cyclitis, selected infective conjunctivitides.

Description –

• Much lower propensity to increase IOP relative to prednisolone acetate or dexamethasone.(Int Ophthalmol. 2012 Oct; 32(5): 507–517.)
• Effective in resolving anterior chamber cells and flare as well as in reducing postoperative pain and discomfort.

Presentation- 5 gm

Dosage Form- Eye Oint.

How to Use – As directed by Physician